Legal botanical opioid type pain killers (7-Hydroxymitragynine, Akuammigine and Hodgkinsine)

Kratom, Akuamma and Sore-mouth Bush have been used as pain-killers in folk medicine practice. Their active principles have been discovered in modern pharmacological and chemistry studies.

The three pain killers and their extract preparations can be purchased online.

Kratom (Mitragyna speciosa) is a tropical evergreen tree and native to Southeast Asia (Indochina, Malesia):

Kratom leaves have psychoactive and are chewed to uplift mood and treat pain and so on health problems.
Kratom leaves have anti-inflammatory and antinociceptive effects.

What's Up Doc?

Sticky patch, oil spray, tablet and capsule for pain-relieving & arthritis control

(Traditional Chinese Medicine formula preparations)

Kratom,  Akuamma and Sore-mouth Bush have been used as pain-killers in folk medicine practice. Their active principles have been discovered in modern pharmacological and chemistry studies.

The three pain killers and their extract preparations can be purchased online.

Kratom (Mitragyna speciosa) is a tropical evergreen tree and native to Southeast Asia (Indochina, Malesia):

  1. Kratom leaves have psychoactive and are chewed to uplift mood and treat pain and so on health problems.
  2. Kratom leaves have anti-inflammatory and antinociceptive effects.
  3. Kratom leaves contain alkaloids 7-hydroxymitragynine and mitragynine which act on various receptors in the brain; mainly on opioid receptors.
  4. 7-Hydroxymitragynine is an opioid agonistic pain killer, 30- and 17-fold higher than that of mitragynine and morphine, respectively.
  5. Mitragynine also acts primarily on μ-opioid receptors.
  6. Kratom does not appear to have significant adverse effects, and appears not to cause the hypoventilation…

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